Celluvisc

Generic Name: ocular lubricant (OK yoo lar LOO bri kant)

Brand Names: Artificial Tears, Celluvisc, Clear Eyes CLR, Comfort Tears, Dry Eye Relief, GenTeal, Isopto Tears, Lacri-Lube S.O.P., Lacrisert, Lubricant Eye Drops, Moisture Drops, Oasis Tears, Opti-Free Rewetting Drops, optive, Refresh, Soothe, Sterilube, Systane, Systane Balance, Tears Again, Tears Naturale, Tears Renew, TheraTears, Ultra Fresh, Visine Tears

What is Celluvisc (ocular lubricant)?

There are many brands and forms of ocular lubricant available and not all are listed on this leaflet.

Ocular lubricant is a solution specially formulated to moisten the eyes.

Ocular lubricant is used to relieve burning, irritation, and discomfort caused by dry eyes.

Ocular lubricant may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Celluvisc (ocular lubricant)?

There are many brands and forms of ocular lubricant available and not all are listed on this leaflet.

You should not use an ocular lubricant if you are allergic to it. Ocular lubricant will not treat or prevent an eye infection.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have any type of infection in your eye.

Do not allow the dropper or tube tip to touch any surface, including the eyes or hands. If the dropper or tube becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Stop using ocular lubricant and call your doctor if you have severe burning, stinging, irritation, eye pain, or vision changes.

This medication may cause blurred vision. Be careful if you drive or do anything that requires you to be able to see clearly.

Talk with your doctor if your symptoms do not improve or if they get worse while you are using ocular lubricant.

What should I discuss with my healthcare provider before using Celluvisc (ocular lubricant)?

You should not use an ocular lubricant if you are allergic to it. Ocular lubricant will not treat or prevent an eye infection.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have any type of infection in your eye.

Ocular lubricant is not expected to harm an unborn baby. Ask a doctor or pharmacist about using ocular lubricant if you are pregnant. It is not known whether ocular lubricant passes into breast milk or if it could harm a nursing baby. Ask a doctor or pharmacist about using ocular lubricant if you are pregnant.

How should I use Celluvisc (ocular lubricant)?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Do not use this medication while wearing contact lenses. Eye medication may contain a preservative that can discolor soft contact lenses. Wait at least 15 minutes after using this medication before putting your contact lenses in. Wash your hands before using ocular lubricant.

To apply the eye drops:

• 
  

  Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper as you squeeze out a drop, then close your eye.

  
  


• 
  

  Use only the number of drops your doctor has prescribed.

  
  


• 
  

  Gently press your finger to the inside corner of the eye (near your nose) for about 1 minute to keep the liquid from draining into your tear duct. If you use more than one drop in the same eye, wait about 5 minutes before putting in the next drop.

  
  


• 
  

  Do not use the eye drops if the liquid has changed colors or has particles in it.

  
  

To apply the ointment:

• 
  

  Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the ointment tube with the tip pointing toward this pocket. Look up and away from the tip.

  
  


• 
  

  Squeeze out a ribbon of ointment 1/2-inch long into the lower eyelid pocket without touching the tip of the tube to your eye. Look down and close your eyes for a few minutes. Rolling your eyes around gently will help spread the ointment evenly.

  
  


• 
  

  After opening your eyes, you may have blurred vision for a short time. Avoid driving or doing anything that requires you to be able to see clearly.

  
  

Do not allow the dropper or tube tip to touch any surface, including the eyes or hands. If the dropper or tube becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Talk with your doctor if your symptoms do not improve or if they get worse while you are using ocular lubricant. Store at room temperature away from moisture and heat. Do not freeze. Keep the bottle or tube tightly closed when not in use.

What happens if I miss a dose?

Since ocular lubricant is used on an as needed basis, you are not likely to miss a dose.

What happens if I overdose?

An overdose of ocular lubricant is not expected to be dangerous.

What should I avoid while using Celluvisc (ocular lubricant)?

This medication may cause blurred vision. Be careful if you drive or do anything that requires you to be able to see clearly.

Avoid using other medications in your eyes during treatment with ocular lubricant unless your doctor tells you to.

Celluvisc (ocular lubricant) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using ocular lubricant and call your doctor if you have a serious side effect such as:

• 
  

  severe burning, stinging, or eye irritation after using the medication;

  
  


• 
  

  eye pain; or

  
  


• 
  

  vision changes.

  
  

Less serious side effects may include:

• 
  

  mild eye burning or irritation;

  
  


• 
  

  itching or redness of your eyes;

  
  


• 
  

  watery eyes;

  
  


• 
  

  blurred vision; or

  
  


• 
  

  unpleasant taste in your mouth.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Celluvisc (ocular lubricant)?

It is not likely that other drugs you take orally or inject will have an effect on ocular lubricant used in the eyes. But many drugs can interact with each other. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

More Celluvisc resources

• Celluvisc Use in Pregnancy & Breastfeeding
• Celluvisc Support Group
• 0 Reviews for Celluvisc - Add your own review/rating

• FreshKote Drops MedFacts Consumer Leaflet (Wolters Kluwer)


• Genteal Advanced Consumer (Micromedex) - Includes Dosage Information


• Lacri-Lube S.O.P. Ointment MedFacts Consumer Leaflet (Wolters Kluwer)


• Lacrisert Prescribing Information (FDA)


• Lacrisert Insert MedFacts Consumer Leaflet (Wolters Kluwer)


• Lacrisert Advanced Consumer (Micromedex) - Includes Dosage Information


• Murine Tears Drops MedFacts Consumer Leaflet (Wolters Kluwer)


• Murocel Eye Drops MedFacts Consumer Leaflet (Wolters Kluwer)


• Refresh Redness Relief Drops MedFacts Consumer Leaflet (Wolters Kluwer)


• Refresh liquigel

Compare Celluvisc with other medications

• Eye Dryness/Redness

Where can I get more information?

• Your pharmacist can provide more information about ocular lubricant.

Pyralvex Liquid

Please read this leaflet carefully before using this product

Pyralvex

PYRALVEX liquid contains rhubarb extract (standardised to contain 0.5% anthraquinone glycosides) and salicylic acid BP 1%. Other ingredients include ethyl alcohol and water.

PYRALVEX does not contain any artificial colourings.

This pack contains 10ml liquid.

Rhubarb extract contains anthraquinone glycosides which relieve inflammation. Salicylic acid is an analgesic which helps to relieve pain.

The product licence for PYRALVEX is held by

Norgine Limited

Moorhall Road

Harefield

Middlesex

UB9 6NS

U.K.

and is manufactured at

Norgine Pharma

29 rue Ethe-Virton B.P. 109

F-28102 DREUX Cedex

France

PYRALVEX brings relief from pain associated with mouth ulcers and denture irritation.

Before you use PYRALVEX.

Do not use PYRALVEX is you are allergic (hypersensitive) to rhubarb extract or salicylic acid or any of the other ingredients of PYRALVEX.

Talk to your doctor before you use PYRALVEX if you are pregnant or breast-feeding.

For hygienic reasons, this pack must only be used by one person.

Not to be used by children under the age of 12 years.

Directions for use

If you wear dentures, remove them before applying PYRALVEX. Using the brush provided, apply PYRALVEX liberally to the sore areas of the mouth 3-4 times daily. Always replace the cap after use.

Avoid rinsing the mouth or eating for 15 minutes after application.

When using PYRALVEX

Being a coloured liquid, PYRALVEX can stain material and care should therefore be taken to ensure that the liquid is not split or dropped onto clothing.

If your symptoms persist for more than 7 days, consult your dentist or doctor.

Like all medicines PYRALVEX can cause side-effects, although not everybody gets them. Very commonly, a short-term burning feeling can occur where PYRALVEX is used. A temporary discolouration of the teeth or mouth can also occur commonly but this is easily removed during normal cleaning of the teeth. If any of the side effects becomes serious, or you notice any side effects not listed in the leaflet, please tell your doctor or pharmacist.

Storage Precautions

Do not use this pack after the expiry date which is shown on the label and carton.

Keep out of the reach and sight of children.

This pack should be stored below 25°C.

Date of last revision 04 January 2008

Insta-Glucose Gel

Pronunciation: GLOO-kose
Generic Name: Glucose
Brand Name: Insta-Glucose

Insta-Glucose Gel is used for:

Treating reactions caused by low blood glucose (sugar).

Insta-Glucose Gel is a monosaccharide (simple sugar). It works by quickly raising the glucose level in the blood.

Do NOT use Insta-Glucose Gel if:

• you are allergic to any ingredient in Insta-Glucose Gel

Contact your doctor or health care provider right away if any of these apply to you.

Before using Insta-Glucose Gel:

Some medical conditions may interact with Insta-Glucose Gel. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Insta-Glucose Gel. However, no specific interactions with Insta-Glucose Gel are known at this time.

Ask your health care provider if Insta-Glucose Gel may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Insta-Glucose Gel:

Use Insta-Glucose Gel as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Insta-Glucose Gel by mouth as directed by your doctor.


• If you miss a dose of Insta-Glucose Gel, contact your doctor right away.

Ask your health care provider any questions you may have about how to use Insta-Glucose Gel.

Important safety information:

• If your symptoms do not get better or if they get worse, check with your doctor.


• Tell your doctor about any low blood sugar reactions.


• Check the expiration date on Insta-Glucose Gel regularly. Replace it so you always have a non-expired product available.


• PREGNANCY and BREAST-FEEDING: Insta-Glucose Gel has not been shown to cause harm to the fetus. It is not known if Insta-Glucose Gel is found in breast milk. If you are or will be breast-feeding while you use Insta-Glucose Gel, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Insta-Glucose Gel:

All medicines may cause side effects, but many people have no, or minor, side effects. No COMMON side effects have been reported with this product. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Insta-Glucose side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Insta-Glucose Gel:

Store Insta-Glucose Gel at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Insta-Glucose Gel out of the reach of children and away from pets.

General information:

• If you have any questions about Insta-Glucose Gel, please talk with your doctor, pharmacist, or other health care provider.


• Insta-Glucose Gel is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Insta-Glucose Gel. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Insta-Glucose resources

• Insta-Glucose Side Effects (in more detail)
• Insta-Glucose Use in Pregnancy & Breastfeeding
• Insta-Glucose Drug Interactions
• Insta-Glucose Support Group
• 0 Reviews for Insta-Glucose - Add your own review/rating

Compare Insta-Glucose with other medications

• Hypoglycemia

Zumenon 2mg

zumenon 2mg


film-coated tablets

What you should know about Zumenon

Please read this leaflet before you take your medicine, and keep it safe because you may want to read it again. If you have any questions or are not sure about anything, ask your doctor or a pharmacist.

What is in Zumenon?

Zumenon belongs to a group of medicines known as Hormone Replacement Therapy or HRT.

Each tablet contains 2 mg estradiol. The tablets are brick-red coloured and can be recognised by the following markings: 'a letter S above a triangle’ on one side and ‘379’ on the other. The estradiol in the tablets is made from plant materials. The tablets also contain: lactose, talc, hypromellose, maize starch, colloidal anhydrous silica, magnesium stearate, macrogol 400, titanium dioxide (E171) and red, black and yellow iron oxides (E172).

Zumenon is available as a three month (84 tablets) calendar pack, which is marked with the days of the week to help you remember to take your tablets.

The marketing authorisation holder is

Solvay Healthcare Limited

Southampton

SO18 3JD

UK

Zumenon is made by

Solvay Biologicals BV

8121 AA Olst

The Netherlands

What is Zumenon for?

Zumenon is an estrogen only continuous HRT for peri and post-menopausal women, used to treat the symptoms of the menopause (change of life). These symptoms vary from woman to woman, and can include hot flushes, night sweats, sleeping difficulties, dryness of the vagina and urinary problems.

Zumenon 2mg may also be used to prevent osteoporosis (thinning of the bones) in women who are at an increased risk of fractures but who are unable to take other medicines for osteoporosis prevention or if these have proved to be ineffective. Your doctor should discuss all the available options with you. Osteoporosis can accelerate after the menopause as estrogen levels fall. If your doctor has prescribed Zumenon for treatment of menopausal symptoms, you will not need to take another medicine to prevent osteoporosis whilst you are taking Zumenon.

Zumenon is suitable for peri and postmenopausal women who may or may not still be having their periods and women switching from standard (cyclic or sequential) HRT on the advice of their doctor.

Zumenon 2 mg is not a contraceptive. If you need contraception you should use a non-hormonal method.

How does Zumenon work?

Zumenon contains estradiol. These hormones replace the estradiol you produce in your ovaries from puberty until the menopause. Your body’s natural estrogen is also called estradiol. Estradiol replaces your body’s natural estrogen, controlling your menopausal symptoms and giving protection against osteoporosis. Women who still have a womb should
normally take some form of progesterone (a progestagen), because estrogen alone can cause problems due to a build up of the womb lining.

When needed, a progestagen such as dydrogesterone 10 mg should normally be added to Zumenon for 12 - 14 days each month. Taking dydrogesterone for part of each monthly cycle (with Zumenon) helps prevent a build up of the womb lining by inducing a regular monthly bleed (see ‘Endometrial cancer’).

Before taking Zumenon

Before you take your medicine, you should make sure that it is safe for you to do so. If you answer yes to any of the following questions,

do not take Zumenon:

• Do you have, have you had, or does your doctor think you might have, breast cancer?


• Have you had or does your doctor think that you might have a tumour which is made worse by estrogens (e.g. endometrial cancer)?


• Do you have or are you being treated for a blood clot in an artery or in a vein in your leg or anywhere else (a deep vein thrombosis), or a blood clot that has travelled to your lung or other parts of your body (an embolus)? Have you had one of these conditions in the past?


• Do you have angina, or have you ever had a heart attack or stroke?


• Has your doctor told you that you have porphyria (a metabolic disorder)?


• Are you allergic to any of the tablet ingredients?

If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.

If any of the following apply to you, you should check with your doctor before you start taking Zumenon:

• you have or have had serious liver disease; or


• you have irregular or unusually heavy periods; or


• you have or have had endometrial hyperplasia; or


• you are pregnant.

Medical check-ups

Before you start taking HRT, your doctor should ask about your own and your family’s medical history. Your doctor may decide to examine your breasts and/or your abdomen, and may do an internal examination - but only if these examinations are necessary for you, or if you have any special concerns.

Once you’ve started on HRT, you should see your doctor for regular check-ups (at least once a year). At these check-ups, your doctor may discuss with you the benefits and risks of continuing to take HRT.

Be sure to:

• 
  go for regular breast screening and cervical smear tests


• 
  regularly check your breasts for any changes such as dimpling of the skin, changes in the nipple,
  or any lumps you can see or feel.

If you have (or had in the past, or are at risk of getting) any of the following conditions, your doctor may want
to see you more often for check-ups:

• fibroids or endometriosis


• blood clots in the legs or lungs


• tumours related to estrogens


• high blood pressure


• liver complaints


• sugar diabetes


• gall stones


• migraine or severe headache


• systemic lupus erythematosus (SLE) (a disease which affects the skin and major organs)


• epilepsy (fits)


• asthma


• otosclerosis (a type of deafness)

Safety of HRT

As well as benefits, HRT has some risks which you need to consider when you’re deciding whether to take it, or whether to carry on taking it.

Effects on your heart or circulation

Heart disease

HRT is not recommended for women who have heart disease, or have had heart disease recently.

If you have had heart disease, talk to your doctor to see if you should take HRT.

HRT will not help to prevent heart disease.

Studies with one type of HRT (containing conjugated estrogen plus the progestagen MPA), have shown that women may be slightly more likely to get heart disease during the first year of taking the medication.

For other types of HRT, the risk is likely to be similar, although this is not yet certain.

If you get:

• a pain in your chest that spreads to your arm or neck

• 
  See a doctor as soon as possible and do not take any more HRT until your doctor says you can. This pain could be a sign of heart disease.

Stroke

Recent research suggests that HRT slightly increases the risk of having a stroke. Other things that can increase the risk of stroke include:

• getting older


• high blood pressure


• smoking


• drinking too much alcohol


• an irregular heartbeat

If you are worried about any of these things, or if you have had a stroke in the past, talk to your doctor to see if you should take HRT.

Compare

Looking at women in their 50s who are not taking HRT - on average, over a 5-year period, 3 in 1000 would be expected to have a stroke.

For women in their 50s who are taking HRT, the figure would be 4 in 1000.

Looking at women in their 60s who are not taking HRT - on average, over a 5-year period, 11 in 1000 would be expected to have a stroke.

For women in their 60s who are taking HRT, the figure would be 15 in 1000.

If you get:

• unexplained migraine-type headaches, with or without disturbed vision

• 
  See a doctor as soon as possible and do not take any more HRT until your doctor says you can. These headaches may be an early warning sign of a stroke.

Blood clots

HRT may increase the risk of blood clots in the veins (also called deep vein thrombosis, or DVT), especially during the first year of taking it.

These blood clots are not always serious, but if one travels to the lungs, it can cause chest pain, breathlessness, collapse or even death.

This condition is called pulmonary embolism, or PE.

DVT and PE are examples of a condition called venous thromboembolism, or VTE.

You are more likely to get a blood clot:

• if you are seriously overweight


• if you have had a blood clot before


• if any of your close family have had blood clots


• if you have had one or more miscarriages


• if you have any blood clotting problem that needs treatment with a medicine such as warfarin


• if you’re off your feet for a long time because of major surgery, injury or illness


• if you have a rare condition called SLE

If any of these things apply to you
, talk to your doctor to see if you should take HRT.

Compare

Looking at women in their 50s who are not taking HRT — on average, over a 5-year period, 3 in 1000 would be expected to get a blood clot.

For women in their 50s who are taking HRT, the figure would be 7 in 1000.

Looking at women in their 60s who are not taking HRT — on average, over a 5-year period, 8 in 1000 would be expected to get a blood clot.

For women in their 60s who are taking HRT, the figure would be 17 in 1000.

If you get:

• painful swelling in your leg


• sudden chest pain


• difficulty breathing

• 
  See a doctor as soon as possible and do not take any more HRT until your doctor says you can. These may be signs of a blood clot.

If you’re going to have surgery,
make sure your doctor knows about it. You may need to stop taking
HRT about 4 to 6 weeks before the operation, to reduce the risk of a blood clot. Your doctor will tell you when you can start taking HRT again.

Effects on your risk of developing cancer

Breast cancer

Women who have breast cancer, or have had breast cancer in the past, should not take HRT.

Taking HRT slightly increases the risk of breast cancer; so does having a later menopause. The risk for a post-menopausal woman taking estrogen-only HRT for 5 years is about the same as for a woman of the same age who’s still having periods over that time and not taking HRT. The risk for a woman who is taking estrogen plus progestagen HRT is higher than for estrogen-only HRT (but estrogen plus progestagen HRT is beneficial for the endometrium, see ‘Endometrial cancer’ below).

For all kinds of HRT, the extra risk of breast cancer goes up the longer you take it, but returns to normal within about 5 years after stopping.

Your risk of breast cancer is also higher:

• if you have a close relative (mother, sister or grandmother) who has had breast cancer


• if you are seriously overweight

Compare

Looking at women aged 50 who are not taking HRT — on average, 32 in 1000 will be diagnosed with
breast cancer by the time they reach the age of 65.

For women who start taking estrogen-only HRT at age 50 and take it for 5 years, the figure will be 33
and 34 in 1000 (i.e. an extra 1-2 cases).

If they take estrogen-only HRT for 10 years, the figure will be 37 in 1000 (an extra 5 cases).

For women who start taking estrogen plus progestagen HRT at age 50 and take it for 5 years, the figure will be 38 in 1000 (i.e. an extra 6 cases).

If they take estrogen plus progestagen HRT for 10 years, the figure will be 51 in 1000 (i.e. an extra 19 cases).

If you


notice

any changes in your breast, such as:

• dimpling of the skin


• changes in the nipple


• any lumps you can see or feel

• 
  Make an appointment to see your doctor as soon as possible.

Endometrial cancer (cancer of the lining of the womb)

Taking estrogen-only HRT for a long time can increase the risk of cancer of the lining of the womb (the endometrium). Taking a progestagen as well as the estrogen helps to lower the extra risk.

If you still have your womb, your doctor may prescribe a progestagen as well as estrogen. If so, these may be prescribed separately, or as a combined HRT product.

If you have had your womb removed (a hysterectomy), your doctor will discuss with you whether you can safely take estrogen without a progestagen.

If you’ve had your womb removed because of endometriosis, any endometrium left in your body may be at risk. So your doctor may prescribe HRT that includes a progestagen as well as an estrogen.

Your product, Zumenon is an estrogen-only product

Compare

Looking at women who still have an uterus and who are not taking HRT – on average 5 in 1000 will be
diagnosed with endometrial cancer between the ages of 50 and 65.

For women who take estrogen-only HRT the number will be 2 to 12 times higher, depending on the dose and how long you take it.

The addition of a progestagen to estrogen-only HRT substantially reduces the risk of endometrial cancer.

If you get

breakthrough bleeding or spotting, it’s usually nothing to worry about, especially during the first few months of taking HRT.

But if the bleeding or spotting:

• carries on for more than the first few months


• starts after you have been on HRT for a while


• carries on even after you have stopped taking HRT

• 
  Make an appointment to see your doctor. It could be a sign that your endometrium has become thicker.

Ovarian cancer

Ovarian cancer (cancer of the ovaries) is very rare, but it is serious. It can be difficult to diagnose, because
there are often no obvious signs of the disease.

Some studies have indicated that taking estrogen-only HRT for more than 5 years may increase the risk of ovarian cancer. It is not yet known whether other kinds of HRT increase the risk in the same way.

Are you taking any of these other medicines?

If you are taking anticonvulsants (e.g. phenobarbital, phenytoin, carbamezapine), anti-infectives (e.g. rifampicin, rifabutin, nevirapine, efavirenz), ritonavir, nelfinavir or herbal preparations containing St John’s Wort (Hypericum perforatum), talk to your doctor or a pharmacist. These other medicines may stop Zumenon working properly.

How to take Zumenon

Generally your doctor will start you on Zumenon 1mg. Your doctor will aim to give you the lowest dose for the shortest time to treat your symptoms. The dose can then be increased, by your doctor, if necessary. Take one tablet every day, without a break between packs. Swallow the tablet with water, with or without food.

In women with an uterus, a progestagen such as dydrogesterone 10 mg should normally be added to Zumenon for 12 - 14 days of each month.

If you are having regular periods you should start taking Zumenon within five days of the start of bleeding.

If you are not having regular periods and are not taking any other HRT preparations, or you are switching from a combined continuous HRT product, you can start taking Zumenon on any convenient day. If you are currently using a ‘cyclic’ or ‘sequential’ HRT preparation (which involves taking an estrogen tablet or patch for part of the month, followed by both estrogen and progestagen tablet or patch for up to 14 days) start taking Zumenon the day after you finish the pack i.e. at the end of the progestagen phase.

If you forget to take a tablet take the next one as soon as you remember. If it is more than 12 hours since you took the last one, take the next dose without taking the forgotten tablet. If you miss a tablet, it is more likely that you will have irregular bleeds.

Overdose

If you (or someone else, e.g. a child) take too many Zumenon tablets, they are unlikely to do any harm. Nausea, vomiting, sleepiness and dizziness may occur. No treatment is necessary, but if you are worried, contact your doctor for advice.

Zumenon 2mg Side Effects

Some women may have side effects when taking Zumenon, but they usually disappear after the first few months. In the list of possible side effects given below, we give an indication of how likely it is that you will get these side effects: ‘common’ means less than one in ten patients may experience this side effect; ‘uncommon’ means less than one in a hundred; ‘rarely’ means less than one in a thousand; and ‘very rarely’ means less than one in ten thousand patients.

Infections: Symptoms of cystitis; thrush; (uncommon)



Tumours: Breast cancer; fibroids get bigger; (uncommon)



Blood changes: Anaemia (iron deficiency); (very rare)



Mental problems: Depression; change in sex drive; nervousness; (uncommon)



Nervous system: Headache; migraine; (common). Dizziness; (uncommon.) Chorea (muscle twitches); (very rare)



Eye changes: Intolerance to contact lenses; change in the surface of the eye; (rare)



Heart: Heart attack; (very rare)



Blood vessels: High blood pressure; peripheral vascular disease; varicose veins; venous thromboembolism (blood clots in the legs, pelvis or lungs); (uncommon). Stroke; (very rare)



Gut complaints: Nausea; abdominal pain; flatulence (wind); (common). Indigestion; (uncommon). Vomiting; (very rare)



Liver complaints: Gall bladder disease; (uncommon). Liver function changes (e.g. jaundice); (rare)



Skin complaints: Allergic skin reactions (including rash or itching); (uncommon). Skin discolouration; swelling or red patches on the skin ;(very rare)



Muscle and bone: Leg cramps; (common). Back pain; (uncommon)



Reproductive system: Tender breasts; irregular bleeds and spotting; pelvic pain; (common). Vaginal discharge; painful periods; heavy or irregular periods; (uncommon). Swollen breasts; pre-menstrual tension (PMT); (rare)



Inherited conditions: Porphyria (a metabolic disorder) gets worse; (very rare)



General complaints: Asthenia (feeling weak); (common). Fluid retention; (uncommon)



Investigations: Weight changes (up or down); (common).

Tumours related to estrogens (both benign and malignant) have been associated with HRT (see ‘Effects on your risk of developing cancer’ above).

Dementia: HRT will not prevent memory loss. In one study of women who started using combined HRT after the age of 65, a small increase in the risk of dementia was observed.

Usually, side effects are not common and do not usually last long. If any of these side effects do last for a long time or you notice any other side effects and you are worried about them, please contact your doctor or a pharmacist for advice.

You should stop taking Zumenon and contact your doctor if:

• you develop any of the conditions listed in the ‘Before taking Zumenon’ section; or


• you develop a blood clot (see ‘Blood clots’); or


• you get sudden problems with your vision, severe headaches or migraines (see ‘Stroke’); or


• you develop jaundice (yellowing of the skin); or


• you become pregnant; or


• your blood pressure increases.

How to store your medicine

Do not store above 30°C. Do not take the tablets after the expiry date shown on the pack. Store all medicines where children cannot see or reach them. Take any unused tablets back to a pharmacy (chemist).

This leaflet was last approved in October 2009.

Remember

This medicine is for you. Please do not offer it to your family and friends, even if they have the same symptoms as you.

For more advice about osteoporosis contact the following organisations:

National Osteoporosis Society

PO Box 10

Radstock

Bath

BA3 3TB

Tel:(01761) 471 771

Helpline:0845 450 0230

registered trade mark

1069707

guanadrel

Generic Name: guanadrel (GWAH na drel)

Brand Names: Hylorel

What is guanadrel?

Guanadrel lowers blood pressure by decreasing the levels of certain chemicals in the blood. This allows the blood vessels (veins and arteries) to relax (widen).

Guanadrel is used to treat hypertension (high blood pressure).

Guanadrel may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about guanadrel?

Do not stop taking guanadrel suddenly without first talking to your doctor. This could cause severely high blood pressure, nervousness, and anxiety. Use caution when driving, operating machinery, or performing other hazardous activities. Guanadrel may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

Use caution when rising from a sitting or lying position, especially first thing in the morning. Dizziness may occur while taking guanadrel and may result in a fall.

What should I discuss with my healthcare provider before taking guanadrel?

Do not take guanadrel without first talking to your doctor if you

• 
  

  have congestive heart failure;

  
  


• 
  

  have pheochromocytoma; or

  
  


• 
  

  are taking a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate).

  
  

Before taking this medication, tell your doctor if you have

• 
  

  peptic ulcer disease (stomach ulcers);

  
  


• 
  

  ulcerative colitis;

  
  


• kidney disease; or


• 
  

  asthma.

  
  

You may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Guanadrel is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Do not take guanadrel without first talking to your doctor if you are pregnant or could become pregnant during treatment. Guanadrel passes into breast milk and it may be harmful to a nursing infant. Do not take guanadrel without first talking to your doctor if you are breast-feeding a baby.

How should I take guanadrel?

Take guanadrel exactly as directed. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. Take guanadrel with food or milk if it causes stomach upset.

It is important to take guanadrel regularly to get the most benefit.

Do not stop taking guanadrel suddenly without first talking to your doctor. This could cause severely high blood pressure, nervousness, and anxiety.

Your doctor may want you to have blood pressure monitoring or other medical evaluations during treatment with guanadrel to monitor progress and side effects.

Store this medication at room temperature away from moisture and heat.

See also: Guanadrel dosage (in more detail)

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the dose you missed and take only the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention if an overdose is suspected.

Symptoms of a guanadrel overdose include low blood pressure (fainting, dizziness, weakness); a slow pulse; low body temperature; diarrhea; and slow breathing.

What should I avoid while taking guanadrel?

Use caution when driving, operating machinery, or performing other hazardous activities. Guanadrel may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

Use caution when rising from a sitting or lying position, especially first thing in the morning. Dizziness may occur while taking guanadrel and may result in a fall.

Avoid alcohol while taking guanadrel. It may increase drowsiness an dizziness caused by guanadrel. Use caution even with small amounts of alcohol.

Guanadrel may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Dangerous sedation, dizziness, or drowsiness may occur if guanadrel is taken with any of these medications. Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor.

Avoid becoming overheated in hot weather or during exercise. Also avoid standing for long periods of time and use caution if you have a fever. These situations increase the effects of guanadrel in the body and may cause dizziness.

Before having surgery, tell your doctor or dentist that you are taking this medication.

Guanadrel side effects

If you experience any of the following serious side effects, stop taking guanadrel and seek emergency medical attention or contact your doctor immediately:

• 
  

  an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);

  
  


• 
  

  irregular heartbeats;

  
  


• 
  

  heart failure (shortness of breath, swelling of ankles or legs, sudden weight gain of 5 pounds or more); or

  
  


• 
  

  chest pain.

  
  

Other, less serious side effects are more likely to occur. Continue to take guanadrel and talk to your doctor if you experience

• 
  

  unusual fatigue or drowsiness;

  
  


• 
  

  dizziness (avoid standing up to quickly and use caution when performing hazardous activities);

  
  


• 
  

  anxiety, depression, or nightmares;

  
  


• 
  

  diarrhea, nausea, or vomiting (take guanadrel with food or milk if it upsets your stomach);

  
  


• 
  

  a stuffy nose or a dry mouth (sucking on ice chips or sugarless hard candy may relieve a dry mouth);

  
  


• 
  

  blurred vision;

  
  


• 
  

  weight gain; or

  
  


• impotence or difficulty ejaculating.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Guanadrel Dosing Information

Usual Adult Dose for Hypertension:

Initial dose: 10 mg/day orally in 1 to 2 divided doses.
Maintenance dose: 20 to 75 mg/day orally in 2 to 4 divided doses.

What other drugs will affect guanadrel?

Do not take guanadrel without first talking to your doctor if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days

Before taking guanadrel, tell your doctor if you are taking any of the following medicines:

• 
  

  a respiratory medicine such as albuterol (Ventolin, Proventil, Volmax, others), pirbuterol (Maxair), salmeterol (Serevent), and others;

  
  


• 
  

  a beta-blocker such as atenolol (Tenormin), acebutolol (Sectral), bisoprolol (Zebeta), carteolol (Cartrol), carvedilol (Coreg), labetalol (Trandate, Normodyne), metoprolol (Lopressor), nadolol (Corgard), propranolol (Inderal), pindolol (Visken), and timolol (Blocadren);

  
  


• 
  

  a phenothiazine such as chlorpromazine (Thorazine), prochlorperazine (Compazine), perphenazine (Trilafon), fluphenazine (Prolixin), thioridazine (Mellaril), and others;

  
  


• 
  

  other heart medications such as hydralazine (Apresoline) or minoxidil (Loniten); or

  
  


• 
  

  a tricyclic antidepressant such as amitriptyline (Elavil, Endep), imipramine (Tofranil), doxepin (Sinequan), nortriptyline (Pamelor), and others.

  
  

You may require special monitoring or a dosage adjustment if you are taking any of the medicines listed above.

Guanadrel may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor.

Drugs other than those listed here may also interact with guanadrel or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

More guanadrel resources

• Guanadrel Side Effects (in more detail)
• Guanadrel Dosage
• Guanadrel Use in Pregnancy & Breastfeeding
• Guanadrel Drug Interactions
• Guanadrel Support Group
• 0 Reviews for Guanadrel - Add your own review/rating

• guanadrel Advanced Consumer (Micromedex) - Includes Dosage Information


• Guanadrel Professional Patient Advice (Wolters Kluwer)

Compare guanadrel with other medications

• High Blood Pressure

Where can I get more information?

• Your pharmacist has additional information about guanadrel written for health professionals that you may read.

What does my medication look like?

Guanadrel is available with a prescription under the brand name Hylorel. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

• 
  

  Hylorel 10 mg--light-orange, elliptical, scored tablets

  
  


• 
  

  Hylorel 25 mg--white, elliptical, scored tablets

  
  

See also: guanadrel side effects (in more detail)

PreNatal Vitamins Plus

Dosage Form: tablet
PreNatal Vitamins Plus

Rx Only

Each Tablet Contains:	Amount per Tablet	% Daily Value
Vitamin A (Acetate and Beta Carotene)	4000 I.U.	80%
Vitamin C (Ascorbic Acid)	120mg.	200%
Vitamin D-3 (Cholecalciferol)	400 I.U.	100%
Vitamin E (dl-Alpha Tocopheryl Acetate)	22 mg.	73%
Vitamin B-1 (Thiamine Mononitrate)	1.84 mg.	123%
Vitamin B-2 (Riboflavin)	3 mg.	176%
Niacin (Niacinamide)	20 mg	100%
Vitamin B-6 (Pyridoxine HCl)	10 mg.	500%
Folic Acid	1 mg.	200%
Vitamin B-12 (Cyanocobalamin)	12 mcg.	200%
Calcium (from Calcium Carbonate)	200 mg.	20%
Iron (Ferrous Fumarate)	27 mg.	150%
Zinc (Zinc Oxide)	25 mg.	167%
Copper (Cupric Oxide)	2 mg.	100%

Other Ingredients: Ascorbyl Palmitate, Citric Acid anhydrous, DL-alpha Tocopherol, Ethylcellulose, FD&C Blue #2 lake, FD&C Red #40 lake, FD&C Yellow #5 lake, FD&C Yellow #6 lake, Glucose, Gum Acacia, Hypromellose, Magnesium Stearate, Maize Starch, Maltodextrin, Methylcellulose, Microcrystalline Cellulose, Mineral Oil, Mono- and di-glycerides, Polyethylene Glycol, Pregelatinized Corn Starch, Silicon Dioxide, Sorbic Acid, Soy Protein, Stearic Acid, Sucrose, Titanium Dioxide, Tricalcium Phosphate.

Indications: To provide vitamin and mineral supplementation throughout pregnancy and during the postnatal period for both the lactating and nonlactating mother. It is also useful for improving nutritional status prior to conception.

Directions: Before, during and after pregnancy, one tablet daily or as directed by a physician.

Contraindications: This product is contraindicated in patients with a known hypersensitivity to any of the ingredients.

Caution: Folic Acid may partially correct the hematological damage due to Vitamin B-12 deficiency of pernicious anemia while the associated neurological damage progresses.

WARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under six. Keep this product out of reach of children. In case of accidental overdose, call a physician or Poison Control Center immediately.

Store at room temperature, USP. Dispense in a well closed light resistant container. KEEP OUT OF THE REACH OF CHILDREN.

Manufactured for:

Boca Pharmacal

Coral Springs, FL 33065

www.bocapharmacal.com

1-800-354-8460

Iss. 02/11

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

NDC 64376-816-01

Bottle of 100 Tablets

[Rev 8]

PreNatal Vitamins Plus  PreNatal Vitamins Plus  tablet

Product Information Product Type HUMAN PRESCRIPTION DRUG NDC Product Code (Source) 64376-816 Route of Administration ORAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength VITAMIN A (VITAMIN A) VITAMIN A 4000 [iU] CHOLECALCIFEROL (CHOLECALCIFEROL) CHOLECALCIFEROL 400 [iU] ZINC (ZINC) ZINC 25 mg THIAMINE MONONITRATE (THIAMINE) THIAMINE MONONITRATE 1.84 mg ASCORBIC ACID (ASCORBIC ACID) ASCORBIC ACID 120 mg CYANOCOBALAMIN (CYANOCOBALAMIN) CYANOCOBALAMIN 12 ug CALCIUM (CALCIUM) CALCIUM 200 mg COPPER (COPPER) COPPER 2 mg FOLIC ACID (FOLIC ACID) FOLIC ACID 1 mg IRON (IRON) IRON 27 mg RIBOFLAVIN (RIBOFLAVIN) RIBOFLAVIN 3 mg NIACIN (NIACIN) NIACIN 20 mg .ALPHA.-TOCOPHEROL ACETATE, DL- (.ALPHA.-TOCOPHEROL ACETATE, DL-) .ALPHA.-TOCOPHEROL ACETATE, DL- 22 mg PYRIDOXINE (PYRIDOXINE) PYRIDOXINE 10 mg

Inactive Ingredients Ingredient Name Strength MINERAL OIL   POLYETHYLENE GLYCOLS   ASCORBYL PALMITATE   ANHYDROUS CITRIC ACID   CELLULOSE, MICROCRYSTALLINE   ACACIA   ETHYLCELLULOSES   FD&C BLUE NO. 2   FD&C RED NO. 40   FD&C YELLOW NO. 5   FD&C YELLOW NO. 6   STARCH, CORN   SILICON DIOXIDE   SORBIC ACID   SOY PROTEIN   STEARIC ACID   SUCROSE   TITANIUM DIOXIDE   TRICALCIUM PHOSPHATE   HYPROMELLOSES   MAGNESIUM STEARATE   MALTODEXTRIN   GLYCERYL MONOSTEARATE   .ALPHA.-TOCOPHEROL, DL-

Product Characteristics Color WHITE (BEIGE) Score no score Shape OVAL (Caplet) Size 19mm Flavor Imprint Code BP;816 Contains

Packaging # NDC Package Description Multilevel Packaging 1 64376-816-01 100 TABLET In 1 BOTTLE None

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
Unapproved drug other		04/15/2011

Labeler - Boca Pharmacal, Inc. (170266089)

Registrant - Boca Pharmacal, Inc. (170266089)

Establishment
Name	Address	ID/FEI	Operations
CISPHARMA INC		833171445	MANUFACTURE

Revised: 04/2011Boca Pharmacal, Inc.

More PreNatal Vitamins Plus resources

• PreNatal Vitamins Plus Use in Pregnancy & Breastfeeding
• Drug Images
• PreNatal Vitamins Plus Drug Interactions
• PreNatal Vitamins Plus Support Group
• 21 Reviews for PreNatal Vitamins Plus - Add your own review/rating

Compare PreNatal Vitamins Plus with other medications

• Vitamin/Mineral Supplementation during Pregnancy/Lactation

Ophthalmic anti-infectives

A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

Ophthalmic anti-infectives are available as eyedrops, gels or ointments and contain antibiotics or antiviral agents. These products are formulated especially to be instilled or applied in the eyes.

Antibiotic eye drops either kill or inhibit the spread of bacteria. They are used to treat ophthalmic bacterial infections such as conjunctivitis or as prophylaxis to prevent infection after eye surgery.

Ophthalmic antivirals act by inhibiting viral replication. These antiviral eye drops are used to slow progression of viral eye infections caused by cytomegalovirus and herpes simplex virus.

See also

Medical conditions associated with ophthalmic anti-infectives:

• Blepharitis
• Blepharoconjunctivitis
• CMV Retinitis
• Conjunctivitis
• Conjunctivitis, Bacterial
• Corneal Ulcer
• Eye Conditions
• Eye Dryness/Redness
• Herpes Simplex Dendritic Keratitis
• Herpetic Keratitis
• Keratitis
• Keratoconjunctivitis
• Neonatal Conjunctivitis
• Ophthalmic Surgery
• Trachoma

Drug List:

Iquix-Drops

Moxeza

Polysporin-Ophthalmic

Tobrex-Drops

Azasite

Vigamox

Ciloxan-Drops

Zymar-Drops

Besivance

Ak-Chlor

Ak-Poly-Bac

Ak-Sulf

Ak-Tob-Drops

Ak-Tracin

Betadine-Ophthalmic

Bleph-10-Drops

Cetamide

Chibroxin

Chloromycetin-Ophthalmic-Ointment

Chloroptic

Chloroptic-S-O-P

Collyrium-Fresh-Ophthalmic

Eyemycin

Gantrisin-Ophthalmic

Garamycin-Ophthalmic

Genoptic-Drops

Gentacidin

Gentak-Drops

Gentasol-Drops

Herplex

Ilotycin

Isopto-Cetamide

Natacyn

Neocidin-Ophthalmic-Ointment

Neocidin

Neocin-Ointment

Neocin-Pg-Drops

Neoptic

Neosporin-Drops

Neosporin-Ophthalmic-Ointment

Ocu-Chlor

Ocu-Mycin

Ocu-Spore-B

Ocu-Spore-G

Ocu-Sul-10

Ocu-Sul-15

Ocu-Sul-30

Ocu-Tracin

Ocuflox-Drops

Ocusulf-10-Drops

Ocutricin

Polycin-B-Ointment

Polytracin-Ophthalmic

Polytrim-Solution

Quixin-Eye-Drops

Romycin-Ointment

Sodium-Sulamyd

Sulf-10

Sulfac-10

Sulfacet-Sodium

Terak-Ointment

Terramycin-With-Polymyxin-B-Ointment

Tobralcon

Tobrasol

Tomycine

Vasosulf

Vira-A

Viroptic-Drops

Vitrasert-Implant

Zirgan

Zymaxid