Dynacirc

Generic Name: isradipine (Oral route)

is-RAD-i-peen

Commonly used brand name(s)

In the U.S.

• Dynacirc


• Dynacirc CR

Available Dosage Forms:

• Tablet


• Tablet, Extended Release


• Capsule

Therapeutic Class: Cardiovascular Agent

Pharmacologic Class: Calcium Channel Blocker

Chemical Class: Dihydropyridine

Uses For Dynacirc

Isradipine is used alone or together with other medicines (such as hydrochlorothiazide) to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled .

Isradipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, isradipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload .

This medicine is available only with your doctor's prescription .

Before Using Dynacirc

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of isradipine in the pediatric population. Safety and efficacy have not been established .

Geriatric

Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of isradipine in the elderly. However, elderly patients are more likely to have liver or kidney problems which may require an adjustment of dose in patients receiving isradipine .

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Bepridil


• Cisapride


• Levomethadyl


• Mefloquine


• Mesoridazine


• Pimozide


• Thioridazine


• Ziprasidone

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acecainide


• Acetophenazine


• Ajmaline


• Amiodarone


• Amisulpride


• Amitriptyline


• Amoxapine


• Aprindine


• Arsenic Trioxide


• Astemizole


• Azimilide


• Bretylium


• Chloral Hydrate


• Chloroquine


• Chlorpromazine


• Clarithromycin


• Dantrolene


• Desipramine


• Dibenzepin


• Disopyramide


• Dofetilide


• Dolasetron


• Doxepin


• Droperidol


• Encainide


• Enflurane


• Erythromycin


• Ethopropazine


• Flecainide


• Fluconazole


• Fluoxetine


• Fluphenazine


• Foscarnet


• Gemifloxacin


• Halofantrine


• Haloperidol


• Halothane


• Hydroquinidine


• Ibutilide


• Imipramine


• Isoflurane


• Lidoflazine


• Lorcainide


• Methotrimeprazine


• Nortriptyline


• Octreotide


• Ondansetron


• Pentamidine


• Perphenazine


• Pipotiazine


• Pirmenol


• Prajmaline


• Probucol


• Procainamide


• Prochlorperazine


• Promazine


• Promethazine


• Propafenone


• Propiomazine


• Protriptyline


• Quetiapine


• Quinidine


• Risperidone


• Sematilide


• Sertindole


• Sotalol


• Spiramycin


• Sulfamethoxazole


• Sultopride


• Tedisamil


• Telithromycin


• Terfenadine


• Thiethylperazine


• Trifluoperazine


• Triflupromazine


• Trimeprazine


• Trimethoprim


• Trimipramine


• Vasopressin


• Zolmitriptan


• Zotepine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Amprenavir


• Dalfopristin


• Indinavir


• Itraconazole


• Ketoconazole


• Magnesium


• Quinupristin


• Rifampin


• Rifapentine


• St John's Wort

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Bowel blockage or


• Congestive heart failure—Use with caution. May make these conditions worse .

• Kidney disease or


• Liver disease—Use with caution. The effects of isradipine may be increased because of the slower removal of the medicine from the body .

Proper Use of isradipine

This section provides information on the proper use of a number of products that contain isradipine. It may not be specific to Dynacirc. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium. Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet .

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well .

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease .

Swallow the extended-release tablet whole with a full glass of water. Do not break, crush, or chew it .

If you are taking the extended-release tablets, part of the tablet may pass into your stools after your body has absorbed the medicine. This is normal and is nothing to worry about .

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For high blood pressure:
  
  • For oral dosage form (capsules):
    
    • Adults—At first, 2.5 milligrams (mg) twice a day. Your doctor may increase your dose if needed.
    
    
    • Children—Use and dose must be determined by your doctor .
    
    
  
  
  • For oral dosage form (extended-release tablets):
    
    • Adults—At first, 5 milligrams (mg) once a day. Your doctor may increase your dose if needed.
    
    
    • Children—Use and dose must be determined by your doctor .
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Dynacirc

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and to check for unwanted effects .

Low blood pressure (hypotension) may occur while taking this medicine. Check with your doctor right away if you have the following symptoms: blurred vision; confusion; severe dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly; sweating; or unusual tiredness or weakness .

This medicine may cause fluid retention (edema) in some patients. Tell your doctor right away if you have bloating or swelling of face, arms, hands, lower legs, or feet; tingling of hands or feet; or unusual weight gain or loss .

Dynacirc Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Bloating or swelling of face, arms, hands, lower legs, or feet


• tingling of hands or feet


• unusual weight gain or loss

Less common

• Chest pain


• difficult or labored breathing


• dizziness


• fast, irregular, pounding, or racing heartbeat or pulse


• feeling of warmth


• full or bloated feeling


• nausea


• pressure in the stomach


• redness of the face, neck, arms and occasionally, upper chest


• shortness of breath


• swelling of abdominal or stomach area


• tightness in chest


• unusual tiredness or weakness


• vomiting


• wheezing

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of Overdose

• Blurred vision


• confusion


• dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly


• flushing


• sweating

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Headache

Less common

• Diarrhea


• difficulty having a bowel movement (stool)


• rash


• stomach soreness or discomfort

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Dynacirc side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Dynacirc resources

• Dynacirc Side Effects (in more detail)
• Dynacirc Use in Pregnancy & Breastfeeding
• Drug Images
• Dynacirc Drug Interactions
• Dynacirc Support Group
• 0 Reviews for Dynacirc - Add your own review/rating

• Dynacirc Concise Consumer Information (Cerner Multum)


• Isradipine Prescribing Information (FDA)


• Isradipine MedFacts Consumer Leaflet (Wolters Kluwer)


• Isradipine Professional Patient Advice (Wolters Kluwer)


• Isradipine Monograph (AHFS DI)


• DynaCirc Prescribing Information (FDA)


• DynaCirc CR Extended-Release Tablets MedFacts Consumer Leaflet (Wolters Kluwer)


• DynaCirc CR Prescribing Information (FDA)

Compare Dynacirc with other medications

• Angina Pectoris Prophylaxis
• High Blood Pressure
• Raynaud's Syndrome

Demerol

Generic Name: meperidine (Oral route)

me-PER-i-deen

Commonly used brand name(s)

In the U.S.

• Demerol


• Meperitab

Available Dosage Forms:

• Syrup


• Solution


• Tablet

Therapeutic Class: Analgesic

Chemical Class: Opioid

Uses For Demerol

Meperidine is used to relieve moderate to severe pain. It belongs to the group of medicines called narcotic analgesics (pain medicines). Meperidine acts on the central nervous system (CNS) to relieve pain. This medicine should not be used to relieve chronic (long-lasting or recurrent) pain.

When meperidine is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely.

This medicine is available only with your doctor's prescription.

Before Using Demerol

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Safety and efficacy of meperidine have not been established in children. However, newborn babies and young infants are more likely to have respiratory depression (very slow breathing), which may require caution in patients receiving meperidine.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of meperidine in the elderly. However, elderly patients are more likely to have age-related kidney or liver problems, which may require caution and an adjustment in the dose for patients receiving meperidine.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Clorgyline


• Iproniazid


• Isocarboxazid


• Linezolid


• Moclobemide


• Naltrexone


• Nialamide


• Pargyline


• Phenelzine


• Procarbazine


• Rasagiline


• Selegiline


• Toloxatone


• Tranylcypromine

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Adinazolam


• Alfentanil


• Alprazolam


• Amobarbital


• Anileridine


• Aprobarbital


• Bromazepam


• Brotizolam


• Buprenorphine


• Butabarbital


• Butalbital


• Butorphanol


• Carisoprodol


• Chloral Hydrate


• Chlordiazepoxide


• Chlorzoxazone


• Cimetidine


• Citalopram


• Clobazam


• Clonazepam


• Clorazepate


• Codeine


• Dantrolene


• Dezocine


• Diazepam


• Estazolam


• Ethchlorvynol


• Fentanyl


• Flunitrazepam


• Fluoxetine


• Flurazepam


• Fospropofol


• Furazolidone


• Halazepam


• Hydrocodone


• Hydromorphone


• Ketazolam


• Levorphanol


• Lorazepam


• Lormetazepam


• Medazepam


• Meperidine


• Mephenesin


• Mephobarbital


• Meprobamate


• Metaxalone


• Methocarbamol


• Methohexital


• Midazolam


• Morphine


• Morphine Sulfate Liposome


• Nalbuphine


• Nitrazepam


• Nordazepam


• Opium


• Oxazepam


• Oxycodone


• Oxymorphone


• Pentazocine


• Pentobarbital


• Phenobarbital


• Prazepam


• Propoxyphene


• Quazepam


• Remifentanil


• Secobarbital


• Sibutramine


• Sodium Oxybate


• Sufentanil


• Tapentadol


• Temazepam


• Thiopental


• Triazolam

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acetophenazine


• Chlorpromazine


• Ethopropazine


• Fluphenazine


• Isoniazid


• Mesoridazine


• Methotrimeprazine


• Perphenazine


• Phenytoin


• Pipotiazine


• Prochlorperazine


• Promazine


• Promethazine


• Propiomazine


• Ritonavir


• Thiethylperazine


• Thioridazine


• Trifluoperazine


• Triflupromazine


• Trimeprazine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

• Ethanol

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Addison's disease (adrenal gland problem) or


• Alcohol abuse, or history of or


• Asthma, severe or


• Brain disease or


• Breathing problems, severe (e.g., hypercapnia, hypoxia) or


• Central nervous system (CNS) depression or


• Chronic obstructive pulmonary disease (COPD) or


• Cor pulmonale (serious heart condition) or


• Drug dependence, especially with narcotics, or history of or


• Enlarged prostate (BPH, prostatic hypertrophy) or


• Head injuries, history of or


• Hypothyroidism (an underactive thyroid) or


• Increased pressure in the head or


• Kyphoscoliosis (severe curvature of the spine with breathing problems) or


• Mental illness, history of or


• Pheochromocytoma (adrenal gland tumor) or


• Problems with passing urine or


• Respiratory depression (very slow breathing) or


• Sickle cell anemia (inherited blood disorder) or


• Weakened physical condition—Use with caution. May increase risk for more serious side effects.

• Heart rhythm problems (e.g., atrial flutter, tachycardia) or


• Hypotension (low blood pressure) or


• Hypovolemia (low blood volume) or


• Seizures, history of—Use with caution. May make these conditions worse.

• Kidney disease or


• Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

• Lung or breathing problems (e.g., respiratory insufficiency), severe or


• Serotonin syndrome—Should not be used in patients with these conditions.

Proper Use of meperidine

This section provides information on the proper use of a number of products that contain meperidine. It may not be specific to Demerol. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. This is especially important for elderly patients, who may be more sensitive to the effects of pain medicines. If too much of this medicine is taken for a long time, it may become habit-forming (causing mental or physical dependence).

Measure the oral liquid with a marked measuring spoon, oral syringe, or medicine cup. Mix each dose of the liquid in 4 ounces (one-half cup) of water and drink all of the water mixture in order to get the correct amount of medicine.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage forms (solution or tablets):
  
  • For moderate to severe pain:
    
    • Adults—50 to 150 milligrams (mg) given every 3 or 4 hours as needed.
    
    
    • Children 1 year of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 1.1 to 1.8 milligrams (mg) per kilogram (kg) of body weight per dose given every 3 or 4 hours as needed.
    
    
    • Children younger than 1 year of age—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Meperidine can cause serious unwanted effects if taken by adults who are not used to strong narcotic pain medicines. Make sure you store the medicine in a safe and secure place to prevent others from getting it.

Flush the unused Demerol® oral liquid or tablets down the toilet.

Precautions While Using Demerol

It is very important that your doctor check the progress of you or your child while you are taking this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you or your child should continue to use it.

Do not use this medicine if you or your child have taken a monoamine oxidase (MAO) inhibitor in the past 2 weeks. MAO inhibitors are used for depression, and some examples are isocarboxazid (Marplan®), phenelzine (Nardil®), selegiline (Eldepryl®), and tranylcypromine (Parnate®). If meperidine is used with MAO inhibitors, you or your child may have unwanted effects like confusion, agitation, restlessness, stomach or intestinal symptoms, a sudden high temperature, an extremely high blood pressure, or convulsions.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that can make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for allergies or colds; sedatives, tranquilizers, or sleeping medicine; other prescription pain medicine or narcotics; medicine for seizures or barbiturates; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the medicines listed above while you or your child are using this medicine.

This medicine may be habit-forming. If you or your child feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions.

Using narcotics for a long time can cause severe constipation. To prevent this, your doctor may direct you or your child to take laxatives, drink a lot of fluids, or increase the amount of fiber in the diet. Be sure to follow the directions carefully, because continuing constipation can lead to more serious problems.

Dizziness, lightheadedness, or fainting may occur when you get up suddenly from a lying or sitting position. Getting up slowly may help lessen this problem. Also, lying down for a while may relieve the dizziness or lightheadedness.

This medicine may make you dizzy, drowsy, confused, or disoriented. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert.

Before having any kind of surgery (including dental surgery) or emergency treatment, tell the medical doctor or dentist in charge that you or your child are using this medicine. Serious unwanted effects can occur if certain medicines are given together with meperidine.

If you have been using this medicine regularly for several weeks or longer, do not change your dose or suddenly stop using it without checking with your doctor. Your doctor may want you or your child to gradually reduce the amount you are using before stopping it completely. This may help prevent worsening of your condition and reduce the possibility of withdrawal symptoms, such as abdominal or stomach cramps, anxiety, fever, nausea, runny nose, sweating, tremors, or trouble with sleeping.

Using this medicine while you are pregnant may cause serious unwanted effects in your newborn baby. Tell your doctor right away if you think you are pregnant or if you plan to become pregnant while using this medicine.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Demerol Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

• Blurred vision


• chest pain or discomfort


• cold, clammy skin


• confusion


• convulsion


• cough


• decrease in the frequency of urination


• decrease in urine volume


• difficult or troubled breathing


• difficulty in passing urine (dribbling)


• difficulty with swallowing


• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position


• fainting


• fast, slow, pounding, or irregular heartbeat or pulse


• fast, weak pulse


• feeling of warmth


• hives


• irregular, fast, slow, or shallow breathing


• itching


• lightheadedness, dizziness, or fainting


• muscle twitching or jerking


• painful urination


• pale or blue lips, fingernails, or skin


• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue


• redness of the face, neck, arms, and occasionally, upper chest


• rhythmic movement of the muscles


• shakiness in the legs, arms, hands, or feet


• shortness of breath


• skin rash


• sweating


• tightness in the chest


• trembling or shaking of the hands or feet


• unconsciousness


• unusual tiredness or weakness


• upper abdominal or stomach pain


• very low blood pressure or pulse


• very slow breathing


• wheezing

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

• Bluish color of the fingernails, lips, skin, palms, or nail beds


• change in consciousness


• decreased awareness or responsiveness


• loss of consciousness


• severe sleepiness


• sleepiness or unusual drowsiness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Drowsiness


• nausea


• relaxed and calm


• vomiting

Incidence not known

• Anxiety


• blurred or loss of vision


• confusion about identity, place, and time


• difficulty having a bowel movement (stool)


• disturbed color perception


• double vision


• dry mouth


• false or unusual sense of well-being


• halos around lights


• headache


• hives or welts


• hyperventilation


• irritability


• nervousness


• night blindness


• overbright appearance of lights


• redness of the skin


• restlessness


• seeing, hearing, or feeling things that are not there


• trouble with sleeping


• tunnel vision


• weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Demerol side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

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More Demerol resources

• Demerol Side Effects (in more detail)
• Demerol Use in Pregnancy & Breastfeeding
• Drug Images
• Demerol Drug Interactions
• Demerol Support Group
• 34 Reviews for Demerol - Add your own review/rating

Compare Demerol with other medications

• Light Sedation
• Pain

Disal

In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Disal

Furosemide

Furosemide monoethanolamine (a derivative of Furosemide) is reported as an ingredient of Disal in the following countries:

• United States

International Drug Name Search

Profemina

Profemina may be available in the countries listed below.

Ingredient matches for Profemina

Conjugated Estrogens

Estrogens, conjugated is reported as an ingredient of Profemina in the following countries:

• Chile

International Drug Name Search

Progeston Depot

Progeston Depot may be available in the countries listed below.

Ingredient matches for Progeston Depot

Hydroxyprogesterone

Hydroxyprogesterone caproate (a derivative of Hydroxyprogesterone) is reported as an ingredient of Progeston Depot in the following countries:

• Japan

International Drug Name Search

Tramadol HCL ActavisGroup

Tramadol HCL ActavisGroup may be available in the countries listed below.

Ingredient matches for Tramadol HCL ActavisGroup

Tramadol

Tramadol hydrochloride (a derivative of Tramadol) is reported as an ingredient of Tramadol HCL ActavisGroup in the following countries:

• Netherlands

International Drug Name Search

Cefcapene pivoxil hydrochloride

Cefcapene pivoxil hydrochloride may be available in the countries listed below.

Ingredient matches for Cefcapene pivoxil hydrochloride

Cefcapene

Cefcapene pivoxil hydrochloride (JAN) is also known as Cefcapene (Rec.INN)

International Drug Name Search

Glossary

JAN	Japanese Accepted Name
Rec.INN	Recommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

Vasoflex

Vasoflex may be available in the countries listed below.

Ingredient matches for Vasoflex

Nimodipine

Nimodipine is reported as an ingredient of Vasoflex in the following countries:

• Chile

Prazosin

Prazosin hydrochloride (a derivative of Prazosin) is reported as an ingredient of Vasoflex in the following countries:

• Bosnia & Herzegowina


• Croatia (Hrvatska)


• Slovenia

International Drug Name Search

Paracétamol Codéine Teva

Paracétamol Codéine Teva may be available in the countries listed below.

Ingredient matches for Paracétamol Codéine Teva

Codeine

Codeine phosphate hemihydrate (a derivative of Codeine) is reported as an ingredient of Paracétamol Codéine Teva in the following countries:

• France

Paracetamol

Paracetamol is reported as an ingredient of Paracétamol Codéine Teva in the following countries:

• France

International Drug Name Search